Green synthesis and antibacterial activity of hydroxyapatite nanorods for orthopedic applications

Biomaterials with antibacterial activity are widely developed for the treatment of bone infection. In the present study, hydroxyapatite (HAp) nanorods were prepared by green synthesis using Azadirachta indica and Coccinia grandis leaf extract. The prepared samples were characterized by various characterization techniques and the results indicate that the prepared samples are constituted of phase pure polycrystalline HAp having hexagonal crystal structure. Moreover, antibacterial activity test confirm that the HAp prepared using leaf extract as a solvent having significant antibacterial activity against Escherichia coli and Staphylococcus aureus. Hence, green synthesis can be a prospective way to develop orthopedic biomaterials with antibacterial properties.